文献简介

出版社:Ocular Immunology & Inflammation

作  者:Yong-Kyu Kim,Se Joon Woo,Yun Jong Lee

编  号:10.3109/09273940903402629

关键字:central retinal vein occlusion | CRVO | MCTD | mixed connective tissue disease | retinal vasculopathy

年  份:2010   点击量:668

文献摘要

Purpose: To report an intractable case of retinal vasculopathy associated with mixed connective tissue disease (MCTD).

研究目的:我们报告一个与混合性结缔组织病(MCTD)相关的棘手视网膜血管病变。

Design: Case report.            

设计:病例报告。

Methods: Interventional case report.

方法:病例报告

Results: A 35-year-old woman presented with decreased visual acuity and multiple retinal hemorrhages and macular edema in her right eye. She had a history of central retinal vein occlusion in the opposite eye and MCTD. Her clinical course deteriorated despite subsequent systemic and intravitreal steroid and immunosuppressant treatments. The retinal vasculopathy involved both artery and vein, causing wide retinal areas of nonperfusion. Her final visual acuity was hand motion.

研究结果:一位35岁的妇女出现视力下降和多个视网膜出血同时伴有右眼黄斑水肿的现象。,她的另一只眼睛曾有过过视网膜中央静脉阻塞的病史且曾患有MCTD。她的临床病程逐渐恶化,尽管随后对他进行了全身性治疗并在玻璃体内注射类固醇同时进行免疫抑制剂的治疗。视网膜血管病变同时涉及动脉和静脉,这造成了广泛的无灌注的视网膜区域。她最终的视力手部动作。

Conclusions: MCTD may be associated with bilateral vasculopathy that is refractory to systemic steroid, intravitreal steroid, and immunosuppressant treatment.

研究结论:MCTD可能与难治的全身性类固醇、玻璃体内的类固醇,以及免疫抑制剂治疗的双侧血管病变相关。