文献简介

出版社:Informa Healthcare

作  者:Amira Zayed, Rehab Mohamed Sobhi & Dalia M. Abdel Halim

编  号:10.3109/09546634.2012.674194

关键字:

年  份:2014   点击量:1511

文献摘要

Background: Despite several therapeutic modalities, acanthosis nigricans (AN) remains a difficult dermatosis to treat. 
背景:

尽管存在很多治疗方法,但是黑棘皮病(AN)仍然是一种很难治愈的皮肤病。
Objective:This study aims to test the safety and efficacy of trichloroacetic acid (TCA) as a chemical peel in the treatment of AN in a random sample of Egyptian female patients.  
目的:

本研究旨在检测三氯乙酸(TCA)作为一种果酸换肤化学制剂,在埃及女性患者的随机样本中,治疗AN的的安全性及有效性。

Method: Six females with AN lesions were included in this pilot study. All patients received chemical peeling sessions using TCA over the affected skin lesions. Sessions were carried out to all patients once per week. Treatment was continued for 1 month. Treatment efficacy was evaluated by determining the average rate of response of the lesions to the treatment on a weekly basis. 
方法:

本次研究纳入6名AN女性患者。所有患者在其皮损受累部位采用TCA进行化学换肤治疗。所有患者每隔一周进行一个疗程。治疗持续1个月。通过测量每周皮损治愈的平均速率来评估其疗效。Results: All patients showed improvement as regard hyperpigmentation, thickening, and the overall appearance. The physician assessment was excellent in three lesions, moderate in five, and was mild in two. No side effects had been reported. Conclusion: The study may present TCA as a safe, easy, and an effective method for the treatment of AN. 

结论:

这项研究表明TCA是一种安全的、简便的、有效的治疗AN的方法。