文献简介

出版社:Blackwell Munksgaard

作  者:Kaushal K.Verma, C.S.Sirka, M.Ramam, V.K Sharma

编  号:

关键字:

年  份:2002   点击量:724

文献摘要

ackground: Persistent photosensitivity after allergic contact dermatitis (ACD) to epoxy resin has rarely been described.

背景:关于变应性接触性皮炎接触环氧树脂后的持续光敏感性鲜有报道

Objective:The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity.

目的:本文研究目的是让人了解到变应性接触性皮炎(ACD)接触到环氧树脂可能触发持续性触发光敏感性。

Methods:We present a series of 5 patients who developed ACD to epoxy resin and later a photo distributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB.

方法:我们提出5名患者的一系列病例,患者出现变应性接触性皮炎(ACD)后接触了环氧树脂,随后暴露在日光下时,出现了沿光照部位分布的湿疹,UVA和UVB治疗下最小的红斑减少。

Results:The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases.Patch testing to epoxy resin was positive in all patients.Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy.

结果:患者的年龄跨度从34岁至71岁,三位男性和两位女性。每位患者均因职业原因接触环氧树脂。3例患者因环氧树脂引发的ACD的症状比光敏性早5个月至12年,2例同时发生。所有患者中对环氧树脂的斑贴试验均为阳性。光试验显示3例进行了光试实验的患者在UVA和UVB治疗后最小红斑的数量都减少。,测试的2例患者中的1例斑贴试验测试环氧树脂为阳性。所有患者在就诊后光敏性仍至少持续了两年,只有1例患者的光敏性因长期避免环氧树脂而消失。
Conclusions:There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.

结论: ACD的情况下接触环氧树脂与光敏性的持续性发展之间存在相关性。探讨了解释这两种现象之间的关系的作用机制。