文献简介

出版社:JAMA Dermatology

作  者:Kevin John Gaddis, MD; Jing Huang, MD; Paul Lawrence Haun, MD, MSc

编  号:

关键字:硬化萎缩苔癣

年  份:2018   点击量:80

文献摘要 全文翻译

A woman in her 60s presented for initial dermatologic evaluation of a 2-year history of a pruritic and sometimes burning hyperpigmented eruption on the bilateral palms. The eruption had gradually spread from the left palm to the right palm and then focally onto the bilateral volar aspect of the wrists in recent months (Figure, A and B). She had not experienced involvement of the plantar surfaces. No additional concerns were reported, and there was no family history of similar lesions. There was no known history of travel in relation to onset of the lesions. Limited clinical examination revealed well-marginated brown atrophic patches on the bilateral palms extending focally onto the volar aspect of the wrist and centrally surmounted by spiny keratotic pits in the palmar creases. Two punch biopsy specimens were obtained for diagnostic clarification (Figure, C and D).

患者女性,60余岁,因进行初步皮肤病学评估就诊,患者有2个月瘙痒病史,双侧掌心色素斑块偶有烧灼感。近几个月来,皮疹逐渐从左侧手掌向右侧手掌扩散,然后在双侧掌腕部聚集(图A和B)。未累及患者足表面。据报道,患者无其他问题,也无类似皮损家族史。患者无与皮损发作相关的旅游史。双侧掌心可见边界清楚的褐色萎缩性斑块,局部延伸至腕部掌侧,周围绕以多棘角化凹陷掌纹。取两个钻孔活检标本用于鉴别诊断(图C和D)。