文献简介

出版社:JAMA

作  者:KarlM.Saardi,MD;ChristineA.DeWitt,MD;MichaelA.Cardis,MD

编  号:

关键字:鱼鳞病

年  份:2020   点击量:188

文献摘要 全文翻译

An African American woman in her 30s presented with a 6-month history of 1-cm to 2-cm erythematous and scaly plaques on her lower legs associated with 30-kg weight loss. The plaques began around her ankles and spread proximally, reaching the upper thighs by the time of presentation. She also noted new lesions on her arms and abdomen in the preceding weeks. The eruption was asymptomatic, and the plaques were preceded by lower extremity edema and weakness, resulting in difficulty ambulating and frequent falls. The patient also reported allodynia, tingling, and numbness in her lower legs. She took no medications and her medical history was significant for a first-trimester miscarriage. She was a schoolteacher and had not traveled outside of the country in the past 10 years.

患者非裔美国女性,30余岁,因下肢6个月1至2cm红斑和鳞屑斑块且体重减轻30公斤而就诊。斑块开始见于脚踝周围,并向近端扩展,就诊时已达到大腿上部。患者自述几周前手臂腹部出现新皮损。皮疹无症状,且斑块出现前双下肢水肿无力,导致行走困难,频繁摔倒。患者还报告称小腿疼痛、刺痛和有麻木感。患者未服用任何药物,且孕早期流产病史意义重大。患者是一名老师,过去10年无出国旅行史。