文献简介

出版社:Journal of Investigative Dermatology

作  者:

编  号:

关键字:银屑病

年  份:2019   点击量:105

文献摘要 全文翻译

Psoriasis is a chronic inflammatory disease of the skin, nails, and joints. In the last two decades, there has been enormous progress in our understanding of the genetics, immunology, and associated comorbidities (Figure 1). This has been accompanied by a marked improvement in the number of therapeutic agents and their effectiveness. Much of this progress has been outlined in numerous articles, commentaries and reviews in the Journal of Investigative Dermatology (JID) over the years (Figure 2). This commentary, which is part of the JID Collections, serves to outline how we have arrived at our present state of knowledge on psoriasis and provides an overview of some exciting future directions.

银屑病是一种皮肤、指甲和关节部位的慢性炎症性疾病。过去的二十年,我们对遗传学、免疫学和相关并发症的了解取得了巨大进步(图1)。与此同时,治疗药物的数量和疗效也有了显著改善。多年来,《皮肤病学研究杂志》(JID)的大量文章、评述和综述概述了大部分进展 (图2)。这是JID 系列的一部分,旨在概述我们对银屑病现有知识的了解现状,并提供银屑病治疗有前景的方向。