文献简介

出版社:International Journal of STD & AIDS

作  者:Y P Tian, L Yao, P Malla, Y Song and S S Li

编  号:10.1258/ijsa.2011.011331

关键字:

年  份:2012   点击量:879

文献摘要

Summary: Giant condyloma acuminatum, or Buschke–Löwenstein tumour, is a unique variant of anogenital warts. It is characterized by locally aggressive behaviour but rarely metastasizes. Many treatment strategies such as radical surgery, radiation and chemotherapy have been used to treat it but their efficacy is often poor and the recurrence rates are high. We report a case of 16- year-old girl who was treated with oral retinoid combined with intramuscular interferon-γ. All lesions cleared within three months. During a follow-up period of more than two years, no recurrence has developed. This relatively painless, non-scarring treatment may represent a novel therapeutic option.

摘要:巨大型尖锐湿疣(或Buschke–Löwenstein肿瘤)是肛门生殖器疣的一种独特变体,其特点是局部性侵略感染,但极少发生转移。许多治疗方法已被用于治疗该疾病,如根治性手术、放射治疗和化学治疗,但往往疗效不佳、复发率高。我们报道了一例口服类维生素A结合肌肉注射γ-干扰素治疗16岁女患者的的病例。该患者所有的病变在三个月内均被清除,在两年多的随访期内,无复发。这种相对无痛、无疤的治疗方法可能提供了一种新的治疗选择。