文献简介

出版社:The International Society of Dermatology

作  者:Carlo Tascini, MD, Enrico Tagliaferri, MD, Gian M. Rossolini, UP, Elisabetta Mantengoli, UP, Gianfranco Mirarchi, MD, Alessandro Leonildi, Res Biol, Marina Polidori, MD, and Francesco Menichetti, CMD

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年  份:2011   点击量:731

文献摘要

Introduction
    Panton–Valentine leukocidin (PVL) is a pore-forming cytotoxin produced by Staphylococcus aureus inducing leukocyte destruction and tissue necrosis.1Although produced by <5% of S. aureus strains, the toxin is detected in large percentages of isolates that cause necrotic skin lesions2–8 and severe necrotizing pneumonia.2,4Although commonly associated with community-acquired methicillin-resistant S. aureus (CA-MRSA),9several outbreaks caused by methicillin-susceptible strains have also been reported.