An 82-year-old woman presented with a longstanding, slowly enlarging annular lesion on the medial aspect of the ankle. Histology confirmed the clinical diagnosis of Porokeratosis of Mibelli. The lesion slowly involuted and resolved over 26 weeks of 5% imiquimod cream applied topically and has not recurred during a 36 month follow-up period.

         一名82岁的女性患者，其脚踝内侧部位出现了一个长期、缓慢扩大的环形病变。组织病理学证实其临床诊断为汗孔角化症。局部应用5％咪喹莫特乳膏26周后，皮损部位渐渐缓解和消退，并且在36个月的随访期内无复发。