文献简介

出版社:Springer-Verlag

作  者:Hee Man Kim Æ Yong-Beom Park Æ Ho Young Maeng

编  号:10.1007/s00296-006-0152-1

关键字:Leukocytoclastic vasculitis,Mycobacterium tuberculosis

年  份:2006   点击量:802

文献摘要

Abstract

摘要

Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we report a 49-year-old male patient that presented with fever, myalgia, and multiple palpable purpura on both of his legs. The biopsy from the purpura yielded a histologic diagnosis of leukocytoclastic vasculitis. The patient had several enlarged lymph nodes on his right neck, and the biopsy revealed tuberculous lymphadenitis.There were no signs of vasculitis present in the internal organs. After antituberculosis treatment, his fever declined and the skin purpura were completely resolved. Although incidence is rare, tuberculosis should be considered as a possible cause of CLV.

   皮肤白细胞破碎性血管炎(CLV)是位于皮肤上的一种小血管炎。多种可能原因导致这种病理状态的存在,包括:药物、感染、胶原血管病和恶性肿瘤。然而,很少有报道称结核杆菌与CLV相关。这里,我们报道了一名49岁的男性患者,伴有发热、肌痛、以及双腿上的多个明显的紫癜样损害。紫癜处皮肤活检得出组织学诊断结果为白细胞破碎性血管炎。在患者的右颈部有一些肿大的淋巴结,并且活检显示为结核性淋巴结炎。其内脏器官没有血管炎存在的迹象。抗结核治疗后,高烧消退,紫癜样皮肤完全恢复。尽管这种疾病的发病率很罕见,但结核病应被视为引发CLV的一个可能原因。