文献简介

出版社:The Korean Academy of Medical Sciences

作  者:Hyo Jin Lee, Dong Hoon Shin, Jong Soo Choi, and Ki Hong Kim

编  号:

关键字:Leukocytoclastic Vasculitis; Influenza A Virus Infection

年  份:2012   点击量:847

文献摘要


Abstract

Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei. Various conditions can cause LCV, and it can be induced by influenza A virus infection. We report a 2-yr-old Korean girl who presented palpable purpuric and hemorrhagic lesions with fever. She was diagnosed as LCV by skin biopsy, and influenza A virus was isolated from nasopharyngeal swab. She was treated with oseltamivir (Tamiflu®) and prednisolone with dramatic effect of vasculitis and fever.

摘要

白细胞破碎性血管炎(LCV)通常表现为明显的紫癜样皮损,以血管壁炎症和细胞核碎裂为特征。许多原因可导致LCV,它可由甲型流感病毒感染诱导产生。我们报道了一名伴有发热症状,出现明显的紫癜样和出血性皮损的2岁韩国女性患儿。皮肤活检诊断为LCV,从患者的鼻咽拭子中分离出甲型流感病毒。血管炎和发热症状在使用奥司他韦(Tamiflu®)和泼尼松龙治疗后获得了惊人的效果。