文献资料 > 掌跖脓疱病
Efficacy of excimer light therapy (308 nm) for palmoplantar pustulosis with the induction of circulating regulatory T cells2013.12.27
准分子光疗法(308纳米)治疗由循环的调节性T细胞诱导的掌跖脓疱病疗效
在这个开放性的研究中,我们探讨使用准分子光(308纳米)(带有过滤器以截止低于297纳米的波长)治疗掌跖脓疱病的疗效。20例掌跖脓疱病患者被纳入本项研究,患者每周治疗一次,共30次。每10次治疗后根据掌跖脓疱病的面积和严重程度指数值(PPPASI)对患者的反应进行评估。...
Novel findings of Langerhans cells and interleukin-17 expression in relation to the acrosyringium and pustule in palmoplantar pustulosis2013.12.27
掌跖脓疱病中朗格汉斯细胞和IL-17的表达与顶端汗管和脓疱相关的新发现
研究背景:掌跖脓疱病是一种慢性、剧烈的炎症性皮肤病,伴有手掌和脚掌局部出现脓疱、红斑和鳞屑。迄今为止,还没有特别的治疗方法。早期的研究结果指出,顶端汗管是炎症的靶点。 Objectives To identify specificfeatures of the PPP inflammatory cell infiltrate and...
Extra-palmoplantar lesions associated with palmoplantar pustulosis2013.12.27
掌跖脓疱病中掌跖之外的病变
掌跖脓疱病(PPP)是一种慢性炎症性疾病,以主要累及在中年女性的手掌和脚掌的无菌性脓疱为特征的。与之相反,除手掌和脚掌以外的其它区域偶尔也会受到影响,表现为类似于银屑病的鳞屑性红疹,有时也能看到单独的脓疱。一些掌跖以外的病变是由克布纳现象诱发或病灶感染后...
Dental Infection as a Triggering Factor in Palmoplantar Pustulosis2013.12.27
牙齿感染作为掌跖脓疱病的一引发因子
掌跖脓疱病(PPP)是一种慢性疾病,以手掌和脚掌出现无菌性脓疱为特征。病灶感染与掌跖脓疱病的恶化紧密相关,常伴有关节痛。扁桃体炎是最常见的罪魁祸首,但关于牙齿感染的报道却十分罕见。在这里我们描述了4例掌跖脓疱病病例,牙齿感染被指出在该疾病的诱发或病情恶化...
掌跖脓疱病治疗进展2013.12.27
对掌跖脓疱病的治疗现状进行综述:免疫抑制剂、维A酸类、糖皮质激素、抗生素、免疫调节剂为当前·临床常用药物,复方甘草酸苷、白芍总苷等亦较常用.,光疗法具有一定优势。合理的联合、交替和序贯治疗有利于疗效最大化。不良反应最小化。
Therapeutic options for palmoplantar pustulosis2013.12.27
Palmoplantar pustulosis (PPP) is a common chronic and recurrent pustular dermatosis characterized by multiple sterile pustules and erythematous plaques on the palms and soles. The exact cause and pathogenesis of the disease remain unknown, and there ...
Concomitant occurrence of acneiform eruption, alopecia areata, and urticaria during adalimumab treatment in a patient with pustulosis palmoplantaris: Case report and literature review2013.12.27
Adalimumab is a fully human immunoglobulin G1 monoclonal antibody against tumor necrosis factor (TNF)-a that is increasingly used for the treatment of many autoimmune diseases. However, it has also been reported that adalimumab can induce many advers...
Management of palmoplantar pustulosis: do we need to change?2013.12.27
Palmoplantar pustulosis (PPP) is difficult to treat. There is little hard evidence for the efficacy of any treatment and no published guidelines for its management. A number of exacerbating factors are well documented and there is some evidence for t...
Ustekinumab in the treatment of palmoplantar pustulosis2013.12.27
MADAM, Palmoplantar pustulosis (PPP) is a challenging disease for dermatologists for which no therapeutic standard has yet been defined.1 Acitretin and psoralen plus ultraviolet A (PUVA) are commonly used; however, virtually all the therapies used in...
Palmoplantar pustulosis with arthro-osteitis: successful treatment with etanercept and acitretin2013.12.27
A 27-year-old male was admitted with pustules on his palms and soles and severe skeletal pain, involving the anterior chest wall, the spine and the sacroiliac region. His skin and skeletal signs and symptoms had started a month earlier. His personal ...
Palmoplantar pustulosis treated with itraconazole: a single, active-arm pilot study2013.12.27
Pustulosis palmoplantaris (PPP; synonyms: pustulosis palmaris et plantaris, palmoplantar amicrobic pustulosis) is a common chronic, relapsing, pustular eruption affecting the palms and soles. The authors report the successful treatment of six therapy...
Association between palmoplantar pustulosis and cigarette smoking in Brazil: a case–control study2013.12.27
Background Palmoplantar pustulosis (PPP) discloses some differences compared to vulgar psoriasis (PV) in terms of age of onset, female predominance and low occurrence of psoriasis lesions elsewhere. Cigarette smoking has been associated to PPP in int...
Patients with palmoplantar pustulosis have increased IL-17 and IL-22 levels both in the lesion and serum2013.12.26
Recent findings about the pathogenesis of pustulosis palmaris et plantaris (PPP), also known as palmoplantar pustulosis, suggest that IL-17 expression in the acrosyringium as well as infiltration of IL-17 positive cells, e.g. Langerhans cells may pla...
Normal and PPP-affected palmoplantar sweat gland express neuroendocrine markers chromogranins and synaptophysin differently2013.12.26
Earlier findings indicate the acrosyringium as the target for the inflammation in the chronic and intensely inflammatory skin disease palmoplantar pustulosis (PPP). The sweat gland apparatus seems to be an immunecompetent structure that probably cont...
Increased peripheral Th17 in patients with pustulosis palmaris et plantaris.02013.12.26
Pustulosis palmaris et plantaris (PPP) is a chronic recurrent dermatitis characterized by intraepidermal pustules with erythematous scaling on the palms and soles. PPP shares many characteristics with psoriasis, but has a diVerent genetic background....
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