文献资料 > 乳房paget病
Extramammary Paget’s Disease: Summary of Current Knowledge2014.01.23
Extramammary Paget’s disease (EMPD) is a rare cutaneous malignancy accounting for approximately 1% to 2% of vulvar cancers.1 Its pathogenesis has been debated, but most cases are thought to arise as a primary intraepidermal neoplasm of glandular ori...
Extra-mammary Paget’s disease of the perianal region: A review of the literature emphasizing the operative management technique2014.01.23
The perianal skin is a common area for extra-mammary Paget’s disease development. The unique clinical,histopathological, and immunohistochemical features which this medical phenomenon demonstrates, along with its rarity and frequent association with...
Effectiveness of photodynamic therapy for mammary and extra-mammary Paget’s disease: a state of the science review2014.01.23
Background: Paget’s disease is a rare skin disorder occurring in the breast (mammary) or in the groin, genital, perianal and axillary regions (extra-mammary). Typical treatment involves surgical excision, which in the case of extramammary Paget’s d...
Extramammary Paget’s disease of the vulva: An annotated review of the current literature2014.01.23
Extramammary Paget’s disease is a rare and unusual neoplastic entity that presents mainly on apocrine gland-bearing skin. The vulva is the most common site of involvement but any area of the anogenital skin can be affected. Due to its rarity, variab...
Extramammary Paget’s disease mimicking acantholytic squamous cell carcinoma in situ: a case report2014.01.23
Background: Extramammary Paget’s disease (EMPD) is an uncommon skin neoplasm characterized by Paget’s cells withpale-staining cytoplasm in the epidermis, and cases with distinguished acantholysis but lacking characteristic Paget’s cells were rarel...
Extramammary Paget’s disease of the Vulva2014.01.23
Vulvar Paget’s disease is an extremely rare neoplasm that accounts for less than 1% of the vulvar malignancies. We present a case of a 75-year-old woman, who had an eczematoid lesion involving the labia majora and minora bilaterally, with infiltrati...
Hybridization Studies on Noninvasive and Invasive Extramammary Paget’s Disease2014.01.23
应用免疫组化和荧光原位杂交方法研究浸润性和非浸润性乳房外Paget氏病
为了确定乳房外Paget病(EMPD)中有效的肿瘤细胞免疫组化标记物,我们对17名EMPD患者,其中包括4名真皮浸润的患者进行免疫组化(IHC)检查。在抗体检查中,所有患者的表皮内和经皮浸润性肿瘤细胞中,细胞角蛋白7(CK7)和CK19呈强阳性。CAM5.2和黏蛋白1(MUC1)也是很好...
Extramammary Paget’s Disease of the Perianal Region: A Review of the Literature Emphasizing Management2014.01.23
肛周部位的乳房外Paget氏病:一则侧重治疗的文献综述
研究背景:肛周Paget氏病是一种罕见的恶性疾病,影响表皮汗腺腺体,其病理通常比较复杂的,伴有一个比较模糊的临床症状,因此诊断往往被延误。尽管自1893年首次被Darier 和 Coulillaud报道已经有100年的时间了,但是恰当的的治疗指南尚未确立。OBJECTIVE To review the ...
35Prognostic Indicators in 35 Patients with Extramammary Paget's Disease2014.01.23
35例乳房外Paget病患者中的预后指标
研究背景: 乳房外Paget病(EMPD)是一种罕见的皮肤肿瘤,通常发生在生殖器部位。目前已经进行了一些关于EMPD的研究。 OBJECTIVE To evaluate the clinicaland pathologic features, treatments, recurrence, survival rates, and prognosticfactors of EMPD. 研究目的:...
Successful Intra-Arterial Chemotherapy for Extramammary Paget’s Disease of the Axilla in a Patient with Parkinson’s Disease2014.01.23
应用动脉灌注化疗成功治愈一位伴有帕金森症的、腋下乳房外Paget氏病的患者
乳房外Paget病(EMPD) 是一种罕见的上皮内肿瘤,在男性患者中发生的频率较低而且发生在腋下更为罕见。一名患有严重的帕金森病的59岁的男性患者表现出腋下EMPD症状。神经系统合并症对EMPD的治疗产生干扰,这促使我们提出在单一短期疗程内采用局部动脉灌注化疗法进行治疗。...
Double anal canal cancers associated with a long history of perianal Paget’s disease: report of a case2014.01.23
Extramammary Paget’s disease (EPD) is rare. We report a case of double anal canal cancers in a patientwith a long history of perianal Paget’s disease. The patient, a 68-year-old Japanese woman, refused surgery initially and was treated with electro...
Ectopic Extramammary Paget's Disease: Case Report and Literature Review2014.01.23
Extramammary Paget's disease that occurs in non-apocrine- bearing regions is referred to as ectopic and has been rarely reported. A 62-year-old man presented with a slowly progressive, asymptomatic light-brown plaque on his back. Histopathologica...
Extramammary Paget’s Disease: Extended Subclinical Growth Detected Using Three-Dimensional Histology in Routine Paraffin Procedure and Course of the Disease2014.01.23
BACKGROUND Extramammary Paget’s disease (EMPD) is a rare tumor of the skin characterized byextended irregular subclinical growth and high recurrence rates after surgery.OBJECTIVE To show that, using three-dimensional (3D) histology in surgical excis...
Reconstruction with scrotal skin fl aps after wide local resection of penoscrotal extramammary Paget ’ s disease2014.01.23
OBJECTIVE• To introduce an effective procedure for reconstruction of large skin defects after wide local resection of penoscrotal extramammary Paget ’ s disease (EMPD) in selected patients using scrotal skin fl aps without compromising oncological ...
A multicenter study on extramammary Paget’s disease in Korea2014.01.23
Background There has been little research on extramammary Paget’s disease (EMPD) conducted in Asia.Methods The aim of this multicenter study was to investigate the clinicopathological features, biological behavior, and treatment of EMPD in 194 Korea...
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