婴儿反复水疱1例
题名: 婴儿反复水疱1例
摘要: An infant boy, born to a nonconsanguineously wed couple, presented to the dermatology outpatient clinic with recurrent skin blisters since age 2 months. The lesions initially started over the trunk and subsequently progressed to involve the face, hands, and feet. The episodes of skin blisters were a...

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Werner综合征
关键词:Werner综合征 Werner's Syndrome

Werner综合征最新文献

A role for the Werner syndrome protein in epigenetic inactivation of the pluripo...2014.03.21
Abstract: Werner syndrome (WS) is an autosomal recessive disorder, the hallmarks of which are premature aging and early onset of neoplastic diseases (Orren, 2006; Bohr, 2008). The gene, whose mutation underlies the WS phenotype, is cal...
The Werner’s Syndrome RecQ Helicase/Exonuclease at the Nexus of Cancer and Agin...2014.03.21
AbstractWerner’s Syndrome (WS) or adult-onset progeria is an autosomal recessive disorder of accelerated aging caused by mutations of the DNA RecQ helicase/exonuclease (WRN). WRN is an ATP-dependent helicase with 3’ to 5’ DNA exonuc...
The Werner Syndrome Protein Suppresses Telomeric Instability Caused by Chromium ...2014.03.21
AbstractTelomeres protect the chromosome ends and consist of guanine-rich repeats coated by specialized proteins. Critically short telomeres are associated with disease, aging and cancer. Defects in telomere replication can lead to tel...
The effect of 2-deoxy-D-glucose on Werner syndrome RecQ helicase gene2014.03.21
Abstract:Caloric restriction (CR) is known to effectively elongate mammalian life-spans. The compound 2- deoxy-D-glucose (2DG), which is often used as an inhibitor of glucose utilization, is a mimetic agent of CR. In this study, we exa...